As a research network, GHGA has multiple cooperations with national and international partners. This ensures a tight embedding within biomedical resarch and the application of international compatible standards for data sharing.
The European Genome-phenome Archive (EGA) is a service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects. GHGA is striving to become the German node within the Federated European Genome-phenome Archive (fEGA). fEGA will be a distributed network of repositories for sharing human omics data and phenotypes. Further Information: https://ega-archive.org/federated
The Global Alliance for Genomics and Health (GA4GH) is an international, nonprofit alliance formed in 2013 to accelerate the potential of research and medicine to advance human health. Bringing together 600+ leading organizations working in healthcare, research, patient advocacy, life science, and information technology, the GA4GH community is working together to create frameworks and standards to enable the responsible, voluntary, and secure sharing of genomic and health-related data.
ELIXIR unites Europe’s leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research. It coordinates, integrates and sustains bioinformatics resources across its member states and enables users in academia and industry to access services that are vital for their research.
The Beyond 1 Million Genomes (B1MG) project is helping to create a network of genetic and clinical data across Europe. The project provides coordination and support to the 1+ Million Genomes Initiative (1+MG). This initiative is a commitment of 23 European countries to give cross-border access to one million sequenced genomes by 2022.
In the National Research Data Infrastructure Germany (NFDI), valuable data from science and research are systematically accessed, networked and made usable in a sustainable and qualitative manner for the entire German science system. Starting in October 2020, GHGA is one of the first nine NFDI consortia and is active in many of the cross-cutting topics within NFDI.
The 'German Network for Bioinformatics Infrastructure – de.NBI' is a national, academic and non-profit infrastructure supported by the Federal Ministry of Education and Research providing bioinformatics services to users in life sciences research and biomedicine in Germany and Europe. The partners organize training events, courses and summer schools on tools, standards and compute services provided by de.NBI to assist researchers to more effectively exploit their data.
The network Single Cell Omics Germany (SCOG) brings together researchers using and developing single cell technologies to generate insights into biomedical systems. Its mission is to provide a collaborative platform for the exchange of both computational and experimental methods and expertise, thereby strengthening single cell research Connecting the German single cell community with relevant international initiatives (such as HCA and IHEC), the network will help to address biomedical questions and foster translational research.
The Next Generation Sequencing Competence Network (NGS-CN) is a Deutsche Forschungsgemeinschaft (DFG) funded initiative that is comprised of four NGS Competence Centers (NGS-CCs), including the West German Genome Center(WGGC), a collaboration led by the University of Cologne that also involves the Universities of Bonn and Düsseldorf; the NGS Competence Center Tübingen (NCCT) at the University of Tübingen; the Dresden-Concept Genome Center (DcGC) at the Technical University Dresden; and the Competence Center for Genomic Analysis Kiel (CCGA) at the University of Kiel.
DeCOI is a national network founded in 3/2020 for the use of NGS-based omics data in COVID-19 research. DeCOI is based on the DFG-funded network of NGS competence centers, bringing together expertise in sequencing and NGS data generation. GHGA and the NFDI4Microbiota Consortium are the other large founding consortia of DeCOI, providing extended expertise in data management and data analysis.
DeCOI is closely connected to the German Biobank Node (GBN), LEOSS, the Helmholtz KI Cooperation Unit, the German Center for Infection Research (DZIF) and the LifeTime Initiative. For the integration of NGS data into international efforts to control COVID-19, DeCOI is also partner of the international COVID-19 host genetics initiative. Therefore, DeCOI is set up as an established network to make a specific contribution to the COVID-19 crisis by utilizing NGS-technologies.
e:Med has the objective of establishing systems medicine in Germany. e:Med promotes system-oriented research into diseases in order to facilitate improved prevention, more comprehensive diagnostics and individually adjusted therapy schemes in individualized medicine. The program brings together scientists with molecular-genetic, clinical, mathematical and information technology expertise, with the objective of ensuring that research results quickly benefit patients.
In addition to the partners mentioned above, GHGA is cooperating with several national and international organizations and stakeholders. In the application process, GHGA received Letters of Support from the following institutions and societies:
European Alliance for Personalised Medicine (EAPM)
Global Alliance for Genomics & Health (GA4GH)
German Network for Bioinformatics Infrastructure (de.NBI)
McGill University - Centre of Genomics and Policy (CGP)
Tryggve and Tryggve 2 Projects
Deutsches Konsortium für Translationale Krebsforschung (DKTK)
European Open Science Cloud (EOSC)
International Cancer Research Consortium, ICGC-ARGO Project
Allianz Chronischer Seltener Erkrankungen (ACHSE)
Nationaler Aktionsplan für Menschen mit Seltenen Erkrankungen (NAMSE)
European Canadian Cancer Network (EUCANCan)
International Human Epigenome Consortium (IHEC)
European Reference Network for Rare Neurological Diseases ERN-RND and European Reference Network for Rare Kidney Diseases (ERKNet)
H2020 Project Solve-RD
Deutsche Gesellschaft für Humangenetik e.V. (GfH)
Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V. (DGGG)
Deutsche Gesellschaft für Innere Medizin e.V. (DGIM)
Deutsche Gesellschaft für Neurologie (DGN)
Deutsche Gesellschaft für Senologie e.V.
Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
Deutsche Krebsgesellschaft e.V. (DKG)
Deutsche Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V.
Institut für Pathologie, Universitätsklinik Dresden
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