Understanding the need to protect sensitive genomic data, GHGA takes a multi-layered approach to data security. Building secure software infrastructure goes hand in hand with building an ethico-legal framework that not only guarantees GDPR-compliance but also a GHGA governance structure developed in exchange with and focused on the patient's needs. GHGA will thereby create clearly defined, democratic access to genomic data for legitimate research purposes - enabling the best research results with sustainable benefits for the health of everyone.
Decentralised collection and storage of human omics data makes it difficult for researchers to find the data they require, or to safely share the results and data that they have generated. GHGA will bring these data together, and make them FAIR - enabling researchers to create new cohorts to help validate their findings and provide opportunities for new and novel Big Data techniques. This will ignite further biological discovery and will help to translate research findings into the clinical routine and disease prevention, benefiting patients as well as public health and adding further value to genomic medicine.
As part of the federated European Genome-Phenome Archive (EGA), GHGA makes data sets easy to find, accessible and optimally usable beyond borders - enabling German researchers to shape future international standards for data exchange and take on leading roles in international research consortia (e.g., the 1+ Million European Genomes Initiative and The Global Alliance for Genomics and Health (GA4GH)).